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doi: 10.1074/jbc.M208727200

doi: 10.3892/ijmm.2017.2932

This "drug-like by design" philosophy has yielded a set of molecular guidelines: 9-11 amino acids, calculated lipophilicity (cLogP) 12.9, at least six N-alkylated amino acids, amide-based cyclization, and avoidance of charged residues