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UVR disrupts microbial equilibrium through direct DNA damage and indirect release of pathogen-associated molecular patterns (PAMPs) and damage-associated molecular patterns (DAMPs), such as oxidized lipids and porphyrins, promoting pathogenic overgrowth (e.g., Staphylococcus aureus )

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Sinn HP, Schneeweiss A, Keller M, Schlombs K, Laible M, Seitz J, et al

Pan-cancer studies further validate IPAs causal role: its supplementation improves ICI response rates across malignancies (110, 159), while ATB-induced microbiota depletion reduces IPA levels and blunts T cell-mediated tumor controlan effect reversed by exogenous IPA, which directly upregulates granzyme B/perforin in T cells (111)

8 Changes in the amygdala have also been linked with anxiety and depressive disorders

rather, they may help contextualize why an individual might explore antioxidant support alongside evidence-based autism interventions