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HIFP limits the transfer of oxygen and nutrients, exacerbating hypoxia and acidity

10.1038/s41586-020-03129-z 20 FangJ.YanY.TengX.WenX.LiN.PengS.et al (2018)

A multitude of non-histone proteins within tumor cells can undergo lactylation modification, thereby participating in multiple biological processes of cells, such as DNA damage response (DDR), transcriptional activity, pentose phosphate pathway (PPP), etc

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