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When healthy cells generate energy (adenosine triphosphate, or ATP) through the mitochondrial electron transport chain, they naturally produce highly reactive oxygen species (ROS) as a metabolic byproduct

Lancet 2004;363:14618

The C3(H 2 O)/C3bFB complex interacts with another serine protease, FC, that cleaves FB into Ba and Bb (enzymatically active) units ( Figure 2C )

10.3969/j.issn.1673-5110.2007.08.067 149 LiQ

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