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This paper aims to summarize recent advances in non-pharmacological treatments for AD, including physical therapy, exercise therapy, cell therapy, and nanoparticles (NPs), and to discuss the research progress and challenges associated with these approaches

L-methylfolate supplementation effectively restores impaired endothelial-dependent vasodilation and enhances endothelial health by converting Hcy to methionine, regardless of dietary deficiencies or genetic polymorphisms that inhibit folic acid processing or L-methylfolate synthesis [31, 104, 108,109,110,111]

doi: 10.1021/np030096l 292 NganN

Microneedle arrays as transdermal and intradermal drug delivery systems: materials science, manufacture and commercial development

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Abstract In schizophrenia patients, glutathione dysregulation at the gene, protein and functional levels, leads to N -methyl-D-aspartate (NMDA) receptor hypofunction