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Figure 2 However, most evidence for these interaction circuits is derived from small cohort studies, tissue-level observations, or preclinical models, and further validation is required to determine their reproducibility across biologically distinct RPL subtypes

In a 2017 RCT by Chan et al, 40 lactoferrin in combination with zinc and vitamin E demonstrated a significant reduction in comedones, inflammatory lesions, and sebum production after 10 weeks of treatment

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This is more than 4 million times the recommended daily intake