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Together, the adoption of a standardized cuprizone administration protocol improved inter-study reliability and by using the C57BL/6 inbred mouse strain, provided better options for conducting studies on transgenic mice, many of which are bred to a C57BL/6 background

That may include therapies designed to promote circulation, reduce local inflammation, and encourage healthier nerve signaling

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There is increasing evidence indicating that genetic factors, reduced expression of related proteins, and defective vesicular transportation are potential causes of autophagy pathway disruptions

Facilitates research into cellular receptor interactions