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PAQR3 regulates endoplasmic reticulum-to-golgi trafficking of COPII vesicle via interaction with Sec13/Sec31 coat proteins

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Interestingly, the first step in de novo pyrimidine biosynthesis mediated by CPSs occurs mainly in mitochondria via CPS1 in K-Ras/LKB1-mutant lung cancer cells 32 (Fig