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In addition, biological interpretation and validation of results requires comprehensive understanding of the relevant field and further experimental confirmation ( in vitro culturing of microorganisms isolated from the faeces followed by looking for the desired compounds in the appropriate microbial extracts ( The development and utilization of suitable analytical techniques capable of integrating multi-omics securely and reliably is further necessitated

However, this can cause damage to surrounding normal tissues due to the heat diffusion

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"L-carnitine exerts a nutrigenomic effect via direct modulation of nuclear receptor signaling in adipocytes, hepatocytes and SKMC, demonstrating its nutritional impact." Nutrition Research , January 2021, Jeukendrup, A E et al