It is indicated for the treatment of various conditions, including rheumatoid arthritis (RA), giant cell arteritis (GCA), systemic juvenile idiopathic arthritis (SJIA), polyarticular juvenile idiopathic arthritis (PJIA), and it has also been used in the treatment of COVID-19
J Exp Med (2008) 205(13):29953006.10.1084/jem.20080462 52 BaccalaRGonzalez-QuintialRSchreiberRDLawsonBRKonoDHTheofilopoulosAN
All data are presented as mean standard deviation (SD)
common variants associated with migraine are functionally involved in mitochondrial metabolism

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And also, interestingly, 3.2 Intrinsic and extrinsic mechanistic factors of mitochondrial function mediating chemoresistance in ALs cells There are also intrinsic and extrinsic factors that affect mitochondrial function and, therefore, mediate therapeutic sensitivity