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32325003) and Academic Promotion Programme of Shandong First Medical University (grant no

doi:10.1128/aac.2.2.84 Donadio S, Maffioli S, Monciardini P, Sosio M, Jabs D (2010) Antibiotic discovery in the twenty-first century: current trends and future perspectives

Journal of Animal Physiology and Animal Nutrition, 88: 229-233, ISSN: 1439-0396

377 B cells undergo multiple steps of maturation before becoming plasma cells and acquiring antibody-secreting capacity, which is critical for defense against recurrent infections