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During the injection process, the needle can inadvertently puncture small blood vessels, leading to bruising and swelling at the injection sites

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PMID 9073154)

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Dark circles are the areas of darker pigmentation that appear beneath the eyes

REDEFINE is an ongoing phase 3 trial acting as market evaluation for both CagriSema and cagrilintide, with 60% randomised to CagriSema, 10% cagrilintide, 10% semaglutide, and 20% placebo, where minimum age at inclusion was 55 years with no upper limit [117]