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C., Hawley C

Reuter, W

Inhibition of NRF2 exacerbates HK-2 cell injury, increases of MDA levels, and enhances ferroptotic cell death [45, 46]

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This in turn, first activates the PI3K/Akt/mTOR, PI3K/Akt/FoxO, or Ras/MAPK/(ERK-1/2) pathways that have important roles in cancer cell growth and carcinogenesis