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Cross-compound receptor-occupancy percentages are deliberately not compared here: occupancy (pRO) is a modeled inference, not a measurement, and Willard 2020 cautions that "calculating pRO values has caveats." Binding affinity is the measured quantity

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The effects of the Tbx1 mutation on brain metabolism were analysed first by reporting the results obtained in PBS-treated Tbx1 +/ and WT brains, followed by those obtained in vB12-treated animals with the same genotypes

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Journal of Neuroendocrinology

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The study concluded that folic acid enhanced cognition and reduced inflammatory markers, though donepezils presence may have influenced the findings (Table 6) (208)

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Hydroxocobalamin offers the advantage over other forms of vitamin B12 of a longer half-life in the body

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