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Recently, baicalein was shown to prevent ferroptosis in erastin-treated PANC1 cells (a human pancreatic cancer cell line) by reducing ferrous iron, inhibiting GSH consumption, and inhibiting GPX4 degradation, thereby suppressing lipid peroxidation

Holm C, Kirchgessner TG, Svenson KL, Fredrikson G, Nilsson S, Miller CG, Shively JE, Heinzmann C, Sparkes RS, Mohandas T, et al

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FIGURE 1 Polyunsaturated fatty acids (PUFAs) are generally deemed to be the most predominant substrates of lipid peroxidation

Wang H, Yu SW, Koh DW, Lew J, Coombs C, Bowers W, et al

On day 6 of the estrous cycle, the mean number of follicles 6 mm was 5.83 0.77 in the Ovagen group and 6.71 0.72 in the Folltropin group, compared to only 3.42 0.55 in the control group