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The Lancet Diabetes & Endocrinology, 9(6), 337-348

Telomeres, the protective caps at the end of DNA strands, shorten over time, leading to cellular ageing and eventual cell death

Alternatively, the activation of DUOXs, with subsequent H 2 O 2 production and neutrophil recruitment, can also be activated by ATP through the P2Y receptor (P2YR)/phospholipase C (PLC) Ca 2+ signalling pathway following wounding in embryonic zebrafish tailfins 73