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1418 At the disease site, there is consistent production of reactive oxygen species (ROS) and proinflammatory cytokines, among which the most important is the transforming growth factor beta-1, largely responsible for the production of collagen in the disease site

These compounds are known to suppress the expression of pro-inflammatory cytokines such as TNF- and IL-6, predominantly through inhibition of the NF-B pathway

These enzymes contribute to the epigenetic regulation of gene expression by catalyzing reactions involved in the demethylation of DNA and histones

Treatment Guidance: Apoprotein measurements can help guide treatment decisions in individuals with dyslipidemia