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33 , e2924 (2017)

Upregulating cellular motility: Peptides like TB4 (TB-500) alter the cellular cytoskeleton, affecting cells' ability to move and change shape

doi: 10.3389/fimmu.2022.955069 Received 28 May 2022 Accepted 04 July 2022 Published 26 July 2022 Volume 13 - 2022 Edited by Grant Schulert, Cincinnati Childrens Hospital Medical Center, United States Reviewed by Naoto Tamura, Juntendo University, Japan

IL-1, IL-17A, TNF and Oncostatin M all induce combinations of MMPs in synovial fibroblasts, which result in degradation of glycosaminoglycans or cartilage in vitro