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Sugino N, Karube-Harada A, Sakata A, Takiguchi S, Kato H: Different mechanisms for the induction of copper-zinc superoxide dismutase and manganese superoxide dismutase by progesterone in human endometrial stromal cells

doi:10.1007/BF00175876

The anesthetic numbs the tissue inside the joint, and the steroid medication reduces inflammation and blocks pain

Eisenberg MA, Werner R, Ries S, Hofstetter WL, Mehran RJ, Papasotiropoulos T, Rice DC, Rajaram R, Steinmann N, Swisher SG , Walsh GL, Vaporciyan AA, Opitz I, Antonoff MB

"Since certain nutritional deficiencies can lead to premature graying, maintaining a nutrient-rich diet can help maintain hair color." In addition, because chronic stress can lead to early graying, reducing daily stressors as well as physical stressors on the hair shaft itself such as heat and chemicals that cause damage is important, she notes

It is done under general anesthesia