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2.5 The Role of Ferroptosis in Hypertension Hypertension is one of the major risk factors of CCVDs (Zhang Y

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doi: 10.1016/j.cell.2017.11.048 50 AlimICaulfieldJTChenYSwarupVGeschwindDHIvanovaEet al

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Additionally, siramesine, a lysosome disrupting agent, and lapatinib, an EGFR inhibitor, elicit ferroptosis in a synergistic manner in breast and lung cancer by altering iron regulation (Ma et al., 2016

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