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Treatment with methylcobalamin or hydroxocobalamin may unmask this condition

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Luciferase activity was quantified using a dual-luciferase assay system (Promega, E1910)

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In Cohort 1, 25 WT and 25 RAMP1/3 KO male mice aged 1220 weeks old were injected intraperitoneally after a 12-hour fast with vehicle, sCT at doses of 3 or 150 nmol/kg, or Cagrilintide at a dose of3 nmol/kg

Two practical points that the numbers alone dont capture: Add water slowly, down the vial wall