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As compared with non-metastatic set up, LOX expression in human HCC cells was significantly enhanced in metastatic set up after interaction with polarized macrophages in vitro

A mutation associated with Arts Syndrome, PRPS1 R196W, exhibits decreased O -GlcNAcylation levels and activity of PRPS1

doi: 10.1038/nrg2348 141 WuY.GongW.WangY.YongT.YangF.LiuW.et al

When cells respond to chronic hyperglycemia, the expression of NOX enzymes is upregulated, activating angiotensin II type 1 receptor (AT1R) and increasing superoxide production [152153]

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(2021a, b) in diabetic db/db mice and high glucose-induced HK-2 cells, AC could improve early renal damage induced by DM through regulating TGF-/Smad signaling pathway, which is implicated in regulating renal fibrosis in chronic kidney disease (Wang et al