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Protective effects of forced exercise against nicotine-induced anxiety, depression and cognition impairment in rat

In a STZ-induced DN rat model, BBR alleviated renal damage by reducing fasting blood glucose levels, kidney-to-body weight ratio, 24-h proteinuria, creatinine (Cr) and blood urea nitrogen (BUN) concentrations

Although it demonstrated low predictive power, this model had the highest AUC among the previously reported models: MELD (0.522), MELD-Na (0.623), MELD 3.0 (0.543), CLIF-ACLF score (0.650), CLIF-C OFs (0.676), and CLIF-SOFA score (0.640)