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How quickly it degrades depends almost entirely on three factors: temperature, light exposure, and bacterial contamination

Restriction of arginine induces antibiotic tolerance in Staphylococcus aureus

Preischemic targeting of HIF prolyl hydroxylation inhibits fibrosis associated with acute kidney injury

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The historical reliance on laparoscopy as the gold standard for diagnosis has also contributed to delays, as access to surgical evaluation may be limited and often reserved for advanced or refractory cases