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Many peptides are broken down in the gastrointestinal tract, which is why peptide drugs are often injected, implanted, or specially formulated rather than simply sprinkled on food

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This mechanism can be exploited to actively accumulate drug molecules inside the cell making peptide-drug conjugates a highly interesting and suitable class of molecules as a cellular drug delivery system (Figure 2) (Vrettos et al., 2018)

Other mild symptoms of this stage of vitamin B12 deficiency include depression, fatigue, anxiety, hair loss, numbness, and poor memory and cognition

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