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Cardioprotective Properties In preclinical heart failure and ischemia-reperfusion models, SLU-PP-332 has shown: Improved cardiac contractility Lower cardiomyocyte apoptosis Enhanced fatty acid oxidation in cardiac tissue Reduced pathologic remodeling and fibrosis These findings suggest potential future use in: Heart failure with preserved or reduced ejection fraction (HFpEF / HFrEF) Cardiac ischemia recovery Post-infarct metabolic support 5

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