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Third, further studies on its composition and pharmacological mechanisms are essential to identify its key active metabolites and support the development of standardized topical or oral formulations with consistent quality and demonstrated activity

, NLR family pyrin domain containing 3 (NLRP3)) that sense pathogen-associated molecular patterns (PAMPs) or damage-associated molecular patterns (DAMPs), such as the accumulation of ROS or the efflux of potassium ions (K + )