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Preclinical Studies Early preclinical studies in rodent obesity models demonstrated that AOD9604 administration reduced body weight and fat mass without affecting food intake, indicating a direct metabolic effect rather than an appetite-suppressing mechanism

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Stress and long work hours made recovery challenging

Of the 50 subjects who survived, 9 subjects (18%) had neurological sequelae at hospital discharge

Shock unresponsive to conventional therapy if adrenocortical insufficiency exists or is suspected