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Description

wherein S508 is substituted with either an A, C, D, E, F, G, H, I, K, L, M, N, P, Q, R, T, V, W, or Y

ATP-dependent reduction of cysteine-sulphinic acid by S

doi: 10.3181/0703-MR-67

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Figure 2 The Intracellular Fate of HMCD-Drug Conjugates As described, for the HMCD or their conjugates to exert its biological activity, it must be cleaved from the albumin adduct