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A deficiency can lead to fatigue, muscle weakness, and a significant loss of appetite

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ANIMAL EXPERIMENTS ESSENTIAL FOR THE UNDERSTANDING OF HUMAN INSULIN-GH-IGF AXIS PHYSIOLOGY Insulin, IGF-I, and IGF-II and Their Receptors Efstratiadis series of knock-outs of the insulin-GH-IGF-axis in mice in the early 1990s clearly confirmed its importance in fetal and postnatal growth and metabolism (21)

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This means considering all aspects of your health, from nutrition and exercise to mental well-being and stress management