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These mutations carried out the conversion of a proto-oncogene into a carcinogenic oncogene, which is responsible for different types of cancer (Marnett, 2000)

Non-thiol compounds and metal(loid)-chelation A number of non-thiol compounds such as organic acid (OAs, including citrate, malate, oxalate, malonate, aconitate, and tartrate) and amino acids and their derivatives (including glycinebetaine/betaine