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10.1089/ars.2008.2407 68 LiangL.-P.PatelM

Circadian misalignment, particularly of the sleep-wake cycle, has been implicated in the pathophysiology of neurodegenerative disorders such as Alzheimers, Parkinsons, and Huntingtons diseases, acting not only as a clinical manifestation but also as an active driver of disease progression (Videnovic and Zee, 2015