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doi: 10.1016/j.freeradbiomed.2016.05.015 [DOI] [PMC free article] [PubMed] [Google Scholar] 16

In addition, patients should be more proactive when they are receiving cyclophosphamide than at other times and should not wait until they have a high fever to get medical assistance

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In contrast, positional polar amine substitutions around the quinolinium core not only improved NNMT inhibition as noted previously, but also enabled favorable passive and active transport across membranes (Tables 4 and 5)