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In neither dosage ST could prevent histological changes in the liver, but the kidney and the heart were not affected

It's not a disease or anything else like that

Am J Clin Nutr (1987) 46(1):8690

Iron, Ferritin, Hereditary Ferritinopathy, and Neurodegeneration

The result in phase 2 clinical trials was 24.2% mean body weight reduction at 48 weeks with the 12mg dose, and the first phase 3 TRIUMPH-4 trial reported an average of 28.7% weight loss at 68 weeks