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Malabsorption of vitamin B12 resulting from structural or functional damage to the stomach, where intrinsic factor is secreted, or to the ileum, where intrinsic factor facilitates vitamin B12 absorption

Isatuximab was selected for clinical development based on its additional ability to induce direct cell death, as demonstrated in both in vitro and ex vivo studies [21]

In 2009, an oxyntomodulin-based multi-agonist peptide with glucagon and GLP-1 agonistic actions were created

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Research observations indicate its influence could be more prominent in obese specimens compared to lean ones

cAMP-dependent protein kinase and lipolysis in rat adipocytes