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However, stress, pollution, poor diet, chronic illness, and aging can significantly reduce glutathione levels

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From a physiological point of view, this barrier is generated not only by the morphological entity, but also by a variety of proteins and enzymes in these cells that work together as a controlled and selective transport and metabolic system, protecting the brain from dangerous polar chemicals in the bloodstream and to maintain a tightly regulated microenvironment for neuronal signaling (Zlokovic, 2008)

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