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Finally, the decrease in acetyl-carnitine levels was correlated with reduced expression of carnitine acetyltransferase (CRAT), an enzyme that catalyzes the exchange of acyl groups between carnitine and CoA

an antioxidant-rich diet may be related to the typically higher, and potentially detrimental, total dose of antioxidants provided in supplements (Reference Koivisto, Paulsen and Paur50)

Resveratrol induces TFEB expression and enhances autophagy, improving insulin sensitivity and reducing hepatic steatosis in animal models, although clinical benefits in humans have thus far been modest