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At this point further modifications catalyzed by aldehyde dehydrogenase and aldo-keto reductase allow to obtain carboxyethylmercapturic acid and 3-hydroxypropylmercapturic acid respectively, which are escreted with urine (Fig

Additional file 16: Table S15

It also gave the second highest DPPH scavenging activity, hydrogen peroxide scavenging activity, and guaicol peroxidase activity of 86.99%, 58.61%, and 0.13 iU/l, respectively

Lipoic acid was found to upregulate the expression of -GCL and other antioxidant enzymes via the activation of the nuclear factor E2-related factor 2 (Nrf2)-dependent pathway (31, 33)

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The voxel was positioned ipsilateral to the TBI injury farther from the impact site and over the left hippocampus identified anatomically on imaging (Fig