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Hit 3 was then selected for structure-activity relationship studies, leading to the identification of structural analogues that retained anti-DENV activity through the disruption of NS3-NS5 interaction

Liu Y, Zhou L, Lv C, Liu L, Miao S, Xu Y, et al

Notably, ferroptosis-resistant FLS exhibited a greater amount of tumor necrosis factor (TNF)-related transcriptome

A cryptic K48 ubiquitin chain binding site on UCH37 is required for its role in proteasomal degradation

MXene-encapsulated ZIF-8@Liposomes for NIR-enhanced photothermal therapy in hepatocellular carcinoma treatment: in vitro, in vivo, and in silico study

Acidity-triggered charge-convertible nanoparticles that can cause bacterium-specific aggregation in situ to enhance photothermal ablation of focal infection