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Chronic functional bowel syndrome worsens gut-brain axis dysfunction, neuroinflammation, cognitive impairment, and vulnerability to dementia

Samples were resuspended in 160 L EPPS buffer (200 mM, pH 8.0) using a probe sonicator (1 1015 pulses, power output 20%) and then digested with LysC (4 L of 0.5 g/L per sample, resuspended in HPLC grade water, Wako-chemicals, Fujifilm #125-05061) for 2 h at 37 C in a shaker incubator

System Xc is a disulfide-bonded heterodimer composed of a non-glycosylated light chain xCT (SLC7A11) and a glycosylated heavy chain CD98hc (SLC3A2) [48]

NIR fluorescence delineates tumor cores, whereas highly sensitive surface-enhanced Raman scattering (SERS) identifies infiltrative margins [151, 152]

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Human commensal Prevotella histicola ameliorates disease as effectively as interferon-beta in the experimental autoimmune encephalomyelitis