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Brain MRI often shows the characteristic Dawsons fingers, whereas spinal cord lesions usually extend to fewer than two vertebral segments

6.6 Inflammatory cytokines and proteinases During intervertebral disc degeneration (IDD), the formation of an inflammatory microenvironment is a core pathological feature (Zheng et al., 2024), but when the AF is damaged, NP antigens are exposed, activating an autoimmune response, leading to infiltration of immune cells such as macrophages and T lymphocytes, and the release of numerous inflammatory mediators (Wang et al., 2024

Large, dense urban areas can be, on average, as much as 10C warmer than surrounding rural areas due to urban structures absorption and re-radiation of solar energy as well as anthropogenic heat sourcesa phenomenon known as the urban heat island effect (Rizwan et al., 2008)

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Improves nutrient transport , which promotes optimal muscle growth