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Description

Free radical chain reactions and polyunsaturated fatty acids in brain lipids

For neuroblastoma (NCT00002730 and NCT00005835), the therapeutic outcomes are undisclosed, and for melanoma (NCT00661336), the trial was discontinued for reasons that remain unknown

2018;14(5):e1007013

These may include hormonal imbalances, liver strain, cardiovascular issues, psychological effects, and more

Originally developed as antimalarial drugs, these compounds inhibit autophagy by blocking autophagosome-lysosome fusion, thereby preventing the degradation of autophagic cargo