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Nevertheless, the homozygote mutant genotype leads to hyperhomocysteinemia only when plasma folate status is low in healthy subjects and in patients with cardiovascular disease, thus subjects with this MTHFR mutation may be sensitive to low folate intake (Christensen et al, 1997

Predrag Sikiric Sven Seiwerth Rudolf Rucman Bozidar Sebecic Stable gastric pentadecapeptide BPC 157 is an anti-ulcer peptidergic agent, proven in clinical trials to be both safe in inflammatory bowel disease (PL-10, PLD-116, PL 14736) and wound healing, stable in human gastric juice, with no toxicity being reported

Wu X., Sinani D., Kim H., Lee J., J

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1A, KU-57788 inhibited ATC cell viability in a dose-dependent manner, with IC 50 values of 15.20 M for 8505C, 18.99 M for Hth-7, 12.62 M for CAL-62, 9.71 M for KHM-5M, and 6.95 M for KMH-2, further supporting the potent anti-tumor activity and effective DNA-PKcs inhibition of KU-57788

Shen R, Pan S, Qi S, Lin X, Cheng S