Moriwaki, L
During deep sleep: Growth hormone secretion peaks, driving tissue repair and muscle recovery The brains glymphatic system clears metabolic waste products, including proteins associated with neurodegeneration Cortisol levels reach their daily minimum, allowing the adrenal system to reset Immune function regenerates Cellular repair mechanisms run at maximum efficiency Most adults spend less time in deep sleep than optimal, and this deficit increases with age, stress, alcohol consumption, and certain medications
Despite being effective in blocking the conversion of DOPA to melanin, hydroquinone monotherapy has moderate effectiveness on hyperpigmentation [76, 77] and is responsible for numerous side effects such as mild erythema, burning sensation, dryness, pruritus, and scaling, making it prohibited for use in cosmetics in a majority of countries [77,78,79,80]
Conversely, a healthy composition of the gut microbiota can contribute to the integrity of the intestinal barrier due to increased expression and induction of the assembly of TJ proteins, activation of mucus synthesis, and antioxidant action
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showed that supplementation with lutein (10 mg), zeaxanthin (2 mg), and meso-zeaxanthin (10 mg) for 12 months improved cognitive abilities and episodic memory in participants [26]