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Collectively, this work proposes an LDH-based strategy that concurrently alleviates pathological acidosis, oxidative stress, mitochondrial dysfunction, and macrophage polarization imbalance, providing a potential nanotherapeutic approach for OA management

Mitotic progression following DNA damage enables pattern recognition within micronuclei

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Swelling can usually be alleviated using compression garments and ice, as well as anti-inflammatory medications