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Stefanelli, T., Malesci, A., Repici, A., Vetrano, S

It can also raise blood calcium levels, which can lead to organ damage (21)

Gene expression studies show it activates DNA repair genes and tumor suppressors like p53 while dialing down genes linked to metastasis

RFC1 , reduced folate carrier 1

Lack of B12 can lead to a wide variety of hematologic, neurologic, and psychiatric disorders, may increase the risk of cardiovascular disease (8) , and cause pseudo-thrombotic microangiopathy following gastrectomy (55)

Scientists have also learned how to develop synthetic peptides (lab made versions), which have been designed to mimic or enhance these natural functions in the body