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10.1007/s00253-012-4494-1 Appl

Since inflammation, alongside oxidative stress, is a major contributor to aging and age-related neurodegeneration, ketone bodies have also been shown to reduce both oxidative stress and inflammatory markers, thereby promoting longevity and alleviating age-associated health issues (Pinto et al., 2018

Several HDACis, such as vorinostat, panobinostat, and entinostat, have been tested either as single agents or in combination with chemotherapy and targeted therapies

Peripheral blood response to multiagent induction therapy Patients with persistent circulating leukemia cells at 7 to 10 days after the initiation of multiagent chemotherapy are at increased risk of relapse, compared with patients who have clearance of peripheral blasts within 1 week of therapy initiation.[149] Rate of clearance of peripheral blasts has been found to be of prognostic significance in both T-cell and B-lineage ALL.[149] Peripheral blood MRD before EOI (day 8, day 15) MRD measured in peripheral blood obtained 1 week after the initiation of multiagent induction chemotherapy has also been evaluated as an early response-to-therapy prognostic factor

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No physiotherapy