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Protective mechanisms of cucumis sativus in diabetes-related modelsof oxidative stress and carbonyl stress

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For mouse inclusion/exclusion, before the start, the enrolled mice were approximately the same age (78 weeks) and were expected to be of similar weight under standardized SPF housing conditions

However, elimination of oxidative stress seems not to be the mechanism underlying the GSSSG-mediated inhibition of LPS-induced proinflammatory gene upregulation