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& Marneros, A

In some dogs and cats, receptor crossover suppresses inhibitory tone, increasing the likelihood of unwanted neurologic side effects

For example, lipid nanoparticle-formulated circular RNA expressing NGF (circNGF) provides sustained protein expression and robust neuroprotection for RGCs, significantly outperforming NGF protein therapy (Jiang et al., 2024)

10.2 Internalization and payload delivery barriers Even when suitable antigens are identified, productive internalization is not guaranteed

In comparison to the control, growth of MRAB isolates in presence of amikacin were significantly reduced from 6 g/ml amikacin for MRAB-1 and -2, and from 8 and 10 g/ml amikacin for MRAB-3 and -4, respectively (B)