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Tieu MT, Lovblom LE, McNamara MG, Mason W, Laperriere N, Millar B-A et al

The peer-reviewed evidence summarized below is drawn from studies of each compound separately

CSE is the only known biosynthetic enzyme for cysteine in mammals, hence its deficiency leads to a dependence on exogenous cysteine

2.3.3 SHU9119 The MTII scaffold has been utilized in many structure-activity relationship studies to develop new melanocortin ligands with different selectivity and potency profiles